Some more Epistasis examples:  Each Gene Pair Affecting the Same Character

 


Punnett Square for the F2 of a dihybrid cross:

  AB Ab aB ab
AB AABB AABb AaBB AaBb
Ab AABb Aabb AaBb Aabb
aB AaBB AaBb aaBb aaBb
ab AaBb Aabb aaBb aabb

 


Description 5:  Complete dominance at both gene pairs, but either gene, when dominant hides the effects of the other gene. 


Example: Seed capsules of Shepard's purse

Allele Definitions:

Gene pair A: triangular (A) is dominant to ovoid (a) 
Gene pair B: triangular (B) is dominant to ovoid (b) 

Interaction:

Dominant allele at either the A or B locus hides the ovoid phenotype


 

Genotype- Phenotype Relationships

A _ _ _ triangular
_ _ B_ triangular
aabb iovoid
 

Looking at the Punnett Square table,  the triangular: ovoid phenotypes would occur in a  15:1 ratio

Phenotype

Genotypes

Ratios

triangular AABB, AaBB, AABb, AaBb, AAbb, Aabb, aaBB, aaBb, 15/16
ovoid  aabb 1/16


Description 6:  Complete dominance at both gene pairs. One gene, when dominant, hides the effects of the second gene.  The second gene, when homozygous recessive, hides the effects of the first gene.  

Example: Feather color in chickens

Allele Definitions:

Gene pair A: color inhibition (A) is dominant to color presence (a)
   
Gene pair B: color (B) dominant to white  (b) 
   

Interaction:  

dominant color inhibition (Aa) or  homozygous white (bb) produce the same phenotype


 

Genotype- Phenotype Relationships

A _ _ _   white
_ _ bb  white
aaB _  colored
 

Looking at the Punnett square table, the white:colored phenotypes would occur in a 13:3 ratio

Phenotype Genotypes Ratios
white AABB, AaBB, AABb, AaBb, AAbb, Aabb, aabb 13/16
colored aaBB, aaBb  3/16

 


Description 7:  Complete dominance for both gene pairs, interactions between both dominants to give a new phenotype.


Example: Fruit shape in summer squash

Allele Definitions:

Gene pair A: Sphere (A) is dominant to long (a)
   
Gene pair B: Sphere (B) is dominant to long (b)
   

Interaction:  

 Dominant sphere (A) interacts with dominant sphere (B) to give disc.  Either dominant sphere allele (A or B) hides the effects of long.


 

Genotype- Phenotype Relationships

A _ B_   disc
A_bb or aaB_ sphere
aabb long
 

Looking at the Punnett square table, the disc, sphere and long phenotypes would occur in a 9:6:1 ratio

Phenotype Genotypes Ratios
disc AABB, AaBB, AABb, AaBb,  9/16
black aaBB, aaBb, AAbb, Aabb 6/16
brown aabb 1/16

Look at still more example of epistasis

Strategy Page
Descriptions 1-4
Descriptions 5-7
Descriptions 8-10
Sample Problems